Dynamic time domain near-infrared optical tomography based on a SPAD camera
Jingjing Jiang, Aldo Di Costanzo Mata, Scott Lindner, Edoardo Charbon, Martin Wolf, Alexander Kalyanov
Abstract
In many clinical applications it is relevant to observe dynamic changes in oxygenation. Therefore the ability of dynamic imaging with time domain (TD) near-infrared optical tomography (NIROT) will be important. But fast imaging is a challenge. The data acquisition of our handheld TD NIROT system based on single photon avalanche diode (SPAD) camera and 11 light sources was consequently accelerated. We tested the system on a diffusive medium simulating tissue with a moving object embedded. With 3D image reconstruction, the moving object was correctly located using only 0.2 s exposure time per source.
Topics & Concepts
Diffuse optical imagingSingle-photon avalanche diodeOpticsComputer scienceComputer visionIterative reconstructionInfraredData acquisitionOptical tomographyTime domainNear-infrared spectroscopyTomographyArtificial intelligencePhysicsDetectorAvalanche photodiodeOperating systemOptical Imaging and Spectroscopy TechniquesPhotoacoustic and Ultrasonic ImagingNon-Invasive Vital Sign Monitoring