Gasdermin D maintains bone mass by rewiring the endo-lysosomal pathway of osteoclastic bone resorption
Mobai Li, Dehang Yang, Huige Yan, Zhibin Tang, Danlu Jiang, Jian Zhang, Zhexu Chi, Wanyun Nie, Wenxuan Zhen, Weiwei Yu, Sheng Chen, Zhen Wang, Qianzhou Yu, Xue Zhang, Fan Yang, Shunwu Fan, Xianfeng Lin, Di Wang
Topics & Concepts
Cell biologyBone resorptionEndosomeOsteoclastBiologyPyroptosisHomeostasisLysosomeCathepsinRANKLSecretionInternal medicineEndocrinologyInflammationImmunologyActivator (genetics)BiochemistryInflammasomeIn vitroMedicineReceptorIntracellularEnzymeInflammasome and immune disordersErythrocyte Function and PathophysiologyAutoimmune and Inflammatory Disorders Research