Pregnancy Outcomes in the Ozanimod Clinical Development Program in Patients With Ulcerative Colitis, Crohn’s Disease, and Relapsing Multiple Sclerosis
Marla C. Dubinsky, Lorna Charles, Krzysztof Selmaj, Giancarlo Comi, Anthony Krakovich, Melissa Rosen, C. Janneke van der Woude, Uma Mahadevan
Abstract
Lay Summary This study evaluated pregnancy outcomes in patients with ulcerative colitis, Crohn’s disease, or multiple sclerosis and in healthy volunteers treated with ozanimod. There was no increased incidence of fetal abnormalities or adverse pregnancy outcomes with ozanimod exposure during early pregnancy.
Topics & Concepts
MedicineUlcerative colitisCrohn's diseaseDiseaseMultiple sclerosisPregnancyInternal medicineCrohn diseaseGastroenterologyInflammatory bowel diseaseDermatologyImmunologyBiologyGeneticsPregnancy and Medication ImpactReproductive System and PregnancyPreterm Birth and Chorioamnionitis