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Changes in hormones, Leukocyte Telomere Length (LTL), and p16<sup>INK4a</sup> expression in SM-exposed individuals in favor of the cellular senescence

Susan K. Ardestani, Tahereh Jamali, Ali Taravati, Hossein Behboudi, Mohamad-Reza Vaez-Mahdavi, Elham Faghihzadeh, Tooba Ghazanfari

2022Drug and Chemical Toxicology11 citationsDOI

Abstract

gene expression have changed significantly in favor of cellular senescence in SM-exposed patients. Therefore, it seems that SM exposure increases biological age compared to chronological age in SM-exposed survivors.

Topics & Concepts

TelomereSenescenceCellular senescenceCellular AgingBiologyHormoneMolecular biologyGeneticsCell biologyDNAPhenotypeGeneEndocrinologyTelomeres, Telomerase, and SenescenceRetinoids in leukemia and cellular processesCircadian rhythm and melatonin
Changes in hormones, Leukocyte Telomere Length (LTL), and p16<sup>INK4a</sup> expression in SM-exposed individuals in favor of the cellular senescence | Litcius