Structure, function, and inhibitor targeting of HIV-1 Nef-effector kinase complexes
Ryan P. Staudt, John J. Alvarado, Lori A. Emert‐Sedlak, Haibin Shi, Sherry T. Shu, Thomas E. Wales, John R. Engen, Thomas E. Smithgall
Abstract
and have the potential to enhance immune recognition of latent viral reservoirs as part of a strategy for HIV clearance.
Topics & Concepts
Immune systemViral replicationBiologyViral life cycleDrug discoveryContext (archaeology)Viral pathogenesisEffectorVirologyImmunologyVirusBioinformaticsPaleontologyHIV Research and TreatmentHIV/AIDS drug development and treatmentHIV/AIDS Research and Interventions