Wild blueberry (<i>V. angustifolium</i>) improves TNFα-induced cell barrier permeability through claudin-1 and oxidative stress modulation in Caco-2 cells
Mirko Marino, Samuele Venturi, Marco Rendine, Marisa Porrini, Claudio Gardana, Dorothy Klimis‐Zacas, Cristian Del Bo’, Patrizia Riso
Abstract
Dietary doses of wild blueberry, rich in bioactive components such as polyphenols, may contribute to support the integrity of the intestinal barrier by preserving claudin-1 expression and reducing markers of oxidative stress.
Topics & Concepts
Oxidative stressClaudinCaco-2Tight junctionPolyphenolChemistryCell biologyBiologyCellBiochemistryAntioxidantBarrier Structure and Function StudiesNeurological Disease Mechanisms and TreatmentsAdvanced Glycation End Products research