Selective mitochondrial antioxidant MitoTEMPO reduces renal dysfunction and systemic inflammation in experimental sepsis in rats
Nishkantha Arulkumaran, Sean Pollen, Robert Tidswell, Charlotte Gaupp, Vera B. M. Peters, Giacomo Stanzani, Timothy Arthur Chandos Snow, Michael R. Duchen, Mervyn Singer
Topics & Concepts
Ex vivoOxidative stressMitochondrial ROSEndocrinologyChemistryInternal medicinePharmacologyMedicineBiochemistryIn vitroInflammasome and immune disordersAcute Kidney Injury ResearchNeutrophil, Myeloperoxidase and Oxidative Mechanisms