Adeno-associated virus perfusion enhanced expression: A commercially scalable, high titer, high quality producer cell line process
Wei Xue, Cameron Fulco, Sha Sha, Nick A. Alden, Jan Panteli, Patrick Hossler, James A. Warren
Abstract
GC/mL. The APEX production platform marks a significant leap forward in the efficient and effective manufacturing of rAAV vector products.
Topics & Concepts
ScalabilityLine (geometry)Process (computing)Cell cultureTiterVirologyVirusCell biologyMaterials scienceComputer scienceBiologyMathematicsOperating systemGeneticsGeometryVirus-based gene therapy researchViral Infectious Diseases and Gene Expression in InsectsCAR-T cell therapy research