Facile fabrication of chitosan/hyaluronic acid hydrogel-based wound closure material Co-loaded with gold nanoparticles and fibroblast growth factor to improve anti-microbial and healing efficiency in diabetic wound healing and nursing care
Xin Liu, Shengwei Peng, Yongju Pei, Yuanyuan Huo, Yadi Zong, Jianwei Ren, Jing Zhao
Abstract
anti-bacterial analyses established that FGF-Au@CS/HA has strong antibacterial effectiveness against gram-positive and gram-negative pathogens. The observation of the present research revealed that prepared FGF-Au@CS/HA hydrogel composites could be a suitable biomaterial for diabetic wound care, potentially improving its antibacterial and healing efficacies.
Topics & Concepts
Hyaluronic acidWound healingChitosanFibroblastMaterials scienceWound closureNanoparticleBiomedical engineeringFabricationNanotechnologyChemistryMedicineSurgeryIn vitroBiochemistryPathologyAlternative medicineAnatomyWound Healing and TreatmentsElectrospun Nanofibers in Biomedical ApplicationsHydrogels: synthesis, properties, applications