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The impact of chemical reactivity on the quality and stability of RNA–LNP pharmaceuticals

Tristan Kovačič, Heinrich Haas, Lior Stotsky‐Oterin, Aleš Štrancar, Urban Bren, Dan Peer

2025Nature Reviews Chemistry12 citationsDOI

Topics & Concepts

WorkflowBiochemical engineeringQuality (philosophy)Risk analysis (engineering)AnalyticsChemistryQuality by DesignReactivity (psychology)Process engineeringPerspective (graphical)Computer scienceStability (learning theory)Raw materialChemical stabilityRaw dataProduction (economics)Process developmentDrug deliveryChemical processChemical industryProcess managementNanotechnologyDrug discoveryManufacturing processProcess analytical technologyDrugWork (physics)AutomationQuality assessmentData analysisChemical productsEngineeringViral Infections and Immunology ResearchRNA and protein synthesis mechanismsRNA Research and Splicing
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