Poncirin, an orally active flavonoid exerts antidiabetic complications and improves glucose uptake activating PI3K/Akt signaling pathway in insulin resistant C2C12 cells with anti-glycation capacities
Md Yousof Ali, Sumera Zaib, Mizanur Rahman, Susoma Jannat, Jamshed Iqbal, Seong Kyu Park, Mun Seog Chang
Topics & Concepts
ChemistryGlycationProtein kinase BAdvanced glycation end-productFructosamineInsulin receptorPI3K/AKT/mTOR pathwayBiochemistryGlucose uptakeInsulinPharmacologyInternal medicineSignal transductionEndocrinologyInsulin resistanceReceptorMedicineAdvanced Glycation End Products researchNatural Antidiabetic Agents StudiesDiet, Metabolism, and Disease