Drug-induced self-assembled nanovesicles for doxorubicin resistance reversal via autophagy inhibition and delivery synchronism
Juan Wang, Liyan Qiu
Abstract
This study provides a promising and powerful strategy to achieve enhanced treatment outcomes for the precise combination therapy.
Topics & Concepts
DoxorubicinIn vivoAutophagyChemistryCytotoxicityPharmacologyDrug deliveryIC50PharmacokineticsApoptosisIn vitroDrugCombination therapyPaclitaxelCancer cellCancerChemotherapyMedicineBiologyBiochemistryInternal medicineOrganic chemistryBiotechnologyAutophagy in Disease and TherapyExtracellular vesicles in diseaseEndoplasmic Reticulum Stress and Disease