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lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements

M. Grace Gordon, Fumitaka Inoue, Beth Martin, Max Schubach, Vikram Agarwal, Sean Whalen, Shiyun Feng, Jingjing Zhao, Tal Ashuach, Ryan Ziffra, Anat Kreimer, Ilias Georgakopoulos‐Soares, Nir Yosef, Chun Ye, Katherine S. Pollard, Jay Shendure, Martin Kircher, Nadav Ahituv

2020Nature Protocols159 citationsDOIOpen Access PDF

Topics & Concepts

BarcodeComputational biologyBiologyReporter geneDNA sequencingGeneRegulatory sequenceFunctional genomicsGeneticsGenomeGenomicsRegulation of gene expressionComputer scienceGene expressionOperating systemRNA and protein synthesis mechanismsGenomics and Chromatin DynamicsRNA modifications and cancer
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