Purity and DNA content of AAV capsids assessed by analytical ultracentrifugation and orthogonal biophysical techniques
Klaus Richter, Christine Wurm, Kim Strasser, J. Bauer, Maria Bakou, Ross VerHeul, Shawn M. Sternisha, Andrea Hawe, Michael Salomon, Tim Menzen, Akash Bhattacharya
Topics & Concepts
CapsidAnalytical UltracentrifugationUltracentrifugeChromatographyParticle sizeChemistrySpectroscopyBiological systemAnalytical Chemistry (journal)Materials sciencePhysicsGeneBiologyQuantum mechanicsBiochemistryPhysical chemistryVirus-based gene therapy researchViral Infectious Diseases and Gene Expression in InsectsViral gastroenteritis research and epidemiology