Serum miR-339-3p as a potential diagnostic marker for non-small cell lung cancer
Keson Trakunram, Pichitpon Chaniad, Sarayut Lucien Geater, Warangkana Keeratichananont, Voravit Chittithavorn, Sumonmal Uttayamakul, Suhaimee Buya, Pritsana Raungrut, Paramee Thongsuksai
Abstract
: MiR-339-3p was significantly upregulated in patients with NSCLC compared with participants without cancer, suggesting a diagnostic prediction value for high-risk individuals. Therefore, miR-339-3p expression could be a potential blood-based biomarker for NSCLC.
Topics & Concepts
Lung cancerTaqManmicroRNAOncologyInternal medicineBiomarkerMedicineConfidence intervalReceiver operating characteristicLogistic regressionMann–Whitney U testArea under the curveReal-time polymerase chain reactionDiagnostic biomarkerCancerBiologyGeneGeneticsMicroRNA in disease regulationCancer-related molecular mechanisms researchCircular RNAs in diseases