Prophylactic use of an anti-activated factor XII monoclonal antibody, garadacimab, for patients with C1-esterase inhibitor-deficient hereditary angioedema: a randomised, double-blind, placebo-controlled, phase 2 trial
Timothy Craig, Markus Magerl, Donald S. Levy, Avner Reshef, William R. Lumry, Inmaculada Martinez‐Saguer, Joshua Jacobs, William H. Yang, Bruce Ritchie, Emel Aygören‐Pürsün, Paul K. Keith, Paula J. Busse, Henrike Feuersenger, Dipti Pawaskar, Iris Jacobs, Ingo Pragst, Mittie K. Doyle
Topics & Concepts
Hereditary angioedemaDouble blindMedicinePlaceboAngioedemaMonoclonal antibodyProphylactic treatmentMonoclonalInternal medicineAntibodyDermatologyGastroenterologyImmunologyPathologyAlternative medicineCoagulation, Bradykinin, Polyphosphates, and AngioedemaHemophilia Treatment and ResearchLymphatic System and Diseases