Individualised neoantigen therapy mRNA-4157 (V940) plus pembrolizumab versus pembrolizumab monotherapy in resected melanoma (KEYNOTE-942): a randomised, phase 2b study
Jeffrey S. Weber, Matteo S. Carlino, Adnan Khattak, Tarek Meniawy, George Ansstas, Matthew H. Taylor, Kevin B. Kim, Meredith McKean, Georgina V. Long, Ryan J. Sullivan, Mark B. Faries, Thuy Tran, C. Lance Cowey, Andrew L. Pecora, Montaser Shaheen, Jennifer Segar, Theresa Medina, Victoria Atkinson, Geoffrey T. Gibney, Jason J. Luke, Sajeve Thomas, Elizabeth I. Buchbinder, Jane A Healy, Mo Huang, Manju Morrissey, Igor Feldman, Vasudha Sehgal, Céline Robert-Tissot, Peijie Hou, Lili Zhu, Michelle Brown, Praveen Aanur, Robert Meehan, Tal Zaks
Topics & Concepts
PembrolizumabMedicineInternal medicineHazard ratioMelanomaClinical endpointOncologyIpilimumabPopulationRandomized controlled trialSurgeryConfidence intervalGastroenterologyCancerImmunotherapyCancer researchEnvironmental healthCutaneous Melanoma Detection and ManagementCancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses