PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program
Masao Hashimoto, Koichi Araki, Maria A. Cardenas, Peng Li, Rohit R. Jadhav, Haydn Kissick, William Henry Hudson, Donald J. McGuire, Rebecca C. Obeng, Andreas Wieland, Judong Lee, Daniel T. McManus, James Ross, Se Jin Im, Junghwa Lee, Jian‐Xin Lin, Bin Hu, Erin E. West, Christopher D. Scharer, Gordon J. Freeman, Arlene H. Sharpe, Suresh S. Ramalingam, Alex Pellerin, Volker Teichgräber, William J. Greenleaf, Christian Klein, Jörg J. Goronzy, Pablo Umaña, Warren J. Leonard, Kendall A. Smith, Rafi Ahmed
Topics & Concepts
Lymphocytic choriomeningitisIL-2 receptorCD8Cytotoxic T cellBlockadeEffectorBiologyInterleukin 21CytokineCell biologyImmunologyT cellCancer researchReceptorImmune systemBiochemistryIn vitroImmune Cell Function and InteractionCAR-T cell therapy researchImmunotherapy and Immune Responses