Biologics in Psoriasis: Updated Perspectives on Long-Term Safety and Risk Management
A Al-Janabi, ZZN Yiu
Abstract
Biologics targeting Th1/Th17 cytokines have revolutionised psoriasis treatment. In addition to treatment effectiveness, it is important to define and understand the long-term risks of biologic therapy in order to guide therapy selection and minimise these risks for patients where possible. This review article summarises available evidence from trial data, observational studies and pharmacovigilance registries to explore key long-term risks of biologic treatment, and how these risks might be managed in clinical practice.
Topics & Concepts
MedicineIntensive care medicineObservational studyPharmacovigilanceRisk analysis (engineering)Risk managementRisk assessmentPsoriasisClinical trialMEDLINESelection (genetic algorithm)Biologic AgentsKey (lock)Clinical PracticeExpert opinionOrder (exchange)Psoriasis: Treatment and PathogenesisSpondyloarthritis Studies and TreatmentsDermatology and Skin Diseases