Asymmetric copper-catalyzed alkynylallylic dimethylamination
Si-Yuan Luo, Guo‐Qiang Lin, Zhi‐Tao He
Abstract
A reliable protocol for asymmetric Cu-catalyzed alkynylallylic dimethylamination is described with the discovery of tetramethyldiaminomethane as a new, stable and convenient surrogate of the dimethylamine nucleophile.
Topics & Concepts
ChemistryDimethylamineNucleophileCatalysisCopperCombinatorial chemistryOrganic chemistryCatalytic C–H Functionalization MethodsAsymmetric Hydrogenation and CatalysisChemical Synthesis and Analysis