A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes
Karen Julie la Cour Karottki, Hooman Hefzi, Songyuan Li, Lasse Ebdrup Pedersen, Philipp N. Spahn, Chintan Joshi, David E. Ruckerbauer, Juan A. Hernández Bort, Alex Thomas, Jae Seong Lee, Nicole Borth, Gyun Min Lee, Helene Faustrup Kildegaard, Nathan E. Lewis
Topics & Concepts
BioproductionCRISPRBiologyGlutamineChinese hamster ovary cellGenome editingMetabolic engineeringFlux (metallurgy)GeneLipogenesisMetabolic pathwayGenome engineeringComputational biologyBiochemistryGeneticsChemistryCell cultureAmino acidOrganic chemistryViral Infectious Diseases and Gene Expression in InsectsCRISPR and Genetic EngineeringMicrobial Metabolic Engineering and Bioproduction