Synthesis, in silico and in vitro studies of piperazinyl thiourea derivatives as apoptosis inducer for the treatment of colorectal carcinoma
Penki V.S. Sashankh, Dorothy Priyanka Dorairaj, Jiaying Chen, Yu-Lan Chang, Kuldeep Chand, Ramasamy Karvembu, Ching‐Ming Chien, Sodio C. N. Hsu
Topics & Concepts
ChemistryCytotoxicityApoptosisEthidium bromideCisplatinIn vitroThioureaBenzamidePiperazineStereochemistryIntercalation (chemistry)Triclinic crystal systemBromideDNABiochemistryCrystallographyCrystal structureInternal medicineOrganic chemistryChemotherapyMedicineSynthesis and biological activityMetal complexes synthesis and propertiesSynthesis and Characterization of Heterocyclic Compounds