Exploring the Potential of Natural Products as Antiparasitic Agents forNeglected Tropical Diseases
Dayanna Orosco, Arturo René Mendoza Salgado, Carlos M. Meléndez
Abstract
Abstract: Recent developments in the use of natural product-based molecules as antiparasitic agents for Malaria, leishmaniasis (LE), Chagas disease (CD), and Human African trypanosomiasis (HAT) are reviewed. The role of diverse plants in developing bioactive species is discussed in addition to analyzing the structural diversity of natural products as active agents and the diverse biological applications in CD, HAT, LE, and Malaria. This review focuses on medicinal chemistry, emphasizing the structural characteristics of natural molecules as bioactive agents against parasitic infections caused by Leishmania, Trypanosoma, and Plasmodium parasites.
Topics & Concepts
LeishmaniasisAntiparasiticMalariaNatural productAntiparasitic agentNeglected tropical diseasesLeishmaniaTropical diseaseProtozoaChagas diseaseBiologyProtozoal diseaseTrypanosomiasisVirologyPharmacologyDiseaseImmunologyMedicineMicrobiologyBiochemistryParasite hostingComputer sciencePathologyWorld Wide WebTrypanosoma species research and implicationsResearch on Leishmaniasis StudiesBioactive Compounds and Antitumor Agents