The protein corona hampers the transcytosis of transferrin-modified nanoparticles through blood–brain barrier and attenuates their targeting ability to brain tumor
Wei Xiao, Yazhen Wang, Huilin Zhang, Yuwei Liu, Rou Xie, Xueqin He, Yang Zhou, Luqing Liang, Huile Gao
Topics & Concepts
TranscytosisBlood–brain barrierEndocytosisTransferrin receptorCell biologyIn vivoEndosomeTransferrinEndocytic cycleIn vitroReceptorChemistryBiologyBiophysicsIntracellularBiochemistryNeuroscienceCentral nervous systemBiotechnologyNanoparticle-Based Drug DeliveryGold and Silver Nanoparticles Synthesis and ApplicationsCharacterization and Applications of Magnetic Nanoparticles