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Photocatalytic functionalizations of alkynes

Neha Chalotra, Jaswant Kumar, Tahira Naqvi, Bhahwal Ali Shah

2021Chemical Communications70 citationsDOI

Abstract

-difunctionalization, annulation, cycloaddition and oxidative reactions to construct numerous key building blocks of natural and pharmaceutically important molecules. In addition, the introduction of photoredox chemistry has successfully been used to deal with the challenges associated with alkyne functionalization such as stereoselective and regioselective control. This article accounts for several visible light mediated functionalization reactions of alkynes, wherein they have been transformed into α-oxo compounds, β-keto sulfoxides, substituted olefins, N-heterocycles, internal alkynes and sulfur containing compounds. The article has been primarily categorized into various sections based on the reaction type with particular attention being paid to mechanistic details, advancement and future applications.

Topics & Concepts

ChemistryRegioselectivityAnnulationPhotoredox catalysisCycloadditionSurface modificationCombinatorial chemistryRadicalAlkyneVicinalPhotocatalysisOrganic chemistryCatalysisPhysical chemistrySulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods
Photocatalytic functionalizations of alkynes | Litcius