Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR–S6K pathway
Jason Y. Park, Myunghoo Kim, Seung Goo Kang, Amber Jannasch, Bruce R. Cooper, Julie A. Patterson, Chang H. Kim
Topics & Concepts
Cell biologyHistone deacetylaseBiologyImmune systemEffectorButyratePI3K/AKT/mTOR pathwayT cellCellular differentiationP70-S6 Kinase 1AcetylationHistoneSignal transductionImmunologyBiochemistryFermentationGeneHelicobacter pylori-related gastroenterology studiesImmune Cell Function and InteractionIL-33, ST2, and ILC Pathways