The Origin of Immunity by Means of Prior Infection and Vaccination with Implications for the Origin of Species
Paul Ola
Abstract
Reality has failed to agree with the expectation that vaccines will solve the COVID-19 problem by preventing onward transmission of the coronavirus known as SARS-CoV-2, which followed logical deductions from inflammatory phenomena in which Mechnikov and his contemporaries described immunity as originating from the elimination of pathogens by a system of cells and substances that has since been named the immune system. But upon illustrating the reality in which we are protected from the pathological manifestations that occur in response to the pathogen in immunological phenomena, it was found to be that in which the pathogen does not cause such pathological manifestations through effects that are due to its mere presence but rather through effects that are due to its influence on pathological mechanisms so that immune mechanisms do not protect us from such pathological manifestations by eliminating the pathogen but rather by making asymptomatic hosting of the pathogen possible. And such protection, which occurs in spite of the presence of the pathogen when the conditions from which it originates are present, is obtained by means of infection with the same pathogen through the attenuation of its causative influence and by means of vaccination through the attenuation of the causative influence of the entity in the vaccine, such as the cowpox virus in Jenner’s vaccine, since it is through the same pathway that pathological mechanisms respond to the causative influences of the pathogen and such an immunologically-linked entity. And it follows from the reality thus illustrated that symptoms fail to appear in spite of infection with the pathogen for as long as either or both of the conditions that give rise to both different but connected paths to the immunity obtained by means of infection with the pathogen and vaccination persist. COVID-19 hospitalizations and death therefore do not surge because variants and sub variants of the coronavirus become capable of being transmitted faster after becoming masters in the art of escaping the system which was logically described as the origin of immunity by the theory Mechnikov and his contemporaries formulated in the absence of such an illustration of reality. Rather, such surges occur because the protective conditions that give rise to immunity by enabling us to host pathogens without symptoms disappear in so many people at about the same time. And the higher likelihood of such conditions that give rise to the single asymptomatic infection pathway in the unvaccinated disappearing than those that give rise to the two asymptomatic infection pathways in the vaccinated explains why the unvaccinated are at greater risk of such unfortunate events. If we will put an end to the severe pathological manifestations which have already claimed the lives of millions prematurely during this pandemic and prevent those such as Ebola and those malignancies that appeared catastrophically in Tasmanian devils and decimated their populations within a short period, an understanding of the immunological nature of the pathological effects of the pathogens that are linked with these manifestations, which will enable us to understand both conditions and keep them stable, must be our topmost research priority now.