CB2 receptor activation inhibits the phagocytic function of microglia through activating ERK/AKT-Nurr1 signal pathways
Qi-wen Han, Qian-Hang Shao, Xiaotong Wang, Kaili Ma, Nai‐Hong Chen, Yu‐He Yuan
Topics & Concepts
Protein kinase BMicrogliaNeuroprotectionReceptorNeuroinflammationSignal transductionCannabinoid receptor type 2PI3K/AKT/mTOR pathwayMAPK/ERK pathwayCell biologyNeurodegenerationLY294002AgonistNuclear receptorOrphan receptorBiologyChemistryPharmacologyCannabinoid receptorInternal medicineImmunologyMedicineBiochemistryInflammationGeneDiseaseTranscription factorNuclear Receptors and SignalingAdenosine and Purinergic SignalingNeuroinflammation and Neurodegeneration Mechanisms