A coumarin-based reversible two-photon fluorescence probe for imaging glutathione near <i>N</i>-methyl-<scp>d</scp>-aspartate (NMDA) receptors
Nahyun Kwon, Chang Su Lim, Dayoung Lee, Gyeongju Ko, Jeongsun Ha, Moonyeon Cho, K.M.K. Swamy, Eunyoung Lee, Dong Joon Lee, Sang‐Jip Nam, Xin Zhou, Hwan Myung Kim, Juyoung Yoon
Abstract
and GSH induced a decrease and an increase in fluorescence emission. Probe 1 can serve as a potential practical imaging tool to get important information on GSH in the brain.
Topics & Concepts
IfenprodilNMDA receptorGlutathioneMoietyChemistryFluorescenceReceptorBiophysicsCoumarinTwo-photon excitation microscopyFluorescence-lifetime imaging microscopyStereochemistryPhotochemistryBiochemistryOrganic chemistryBiologyQuantum mechanicsPhysicsEnzymeSulfur Compounds in BiologyMolecular Sensors and Ion DetectionLanthanide and Transition Metal Complexes