Cross-Frequency Coupling in Childhood Absence Epilepsy
Jeffrey R. Tenney, Brady J. Williamson, Darren S. Kadis
Abstract
Cortical regions commonly identified as being critical for absence seizure generation (frontal cortex, precuneus) have strong CFC and within-frequency coupling between beta and gamma bands. As nonpharmacologic treatments, such as neuromodulation, become available for generalized epilepsies, detailed mechanistic understanding of how "diffuse" seizures are generated and maintained will be necessary to provide optimal outcomes.
Topics & Concepts
MagnetoencephalographyIctalNeurosciencePrecuneusPsychologyFunctional magnetic resonance imagingElectroencephalographyEpilepsyConnectomeConnectomicsCortex (anatomy)Coupling (piping)PhysicsFunctional connectivityEngineeringMechanical engineeringEEG and Brain-Computer InterfacesFunctional Brain Connectivity StudiesNeural dynamics and brain function