SPC-180002, a SIRT1/3 dual inhibitor, impairs mitochondrial function and redox homeostasis and represents an antitumor activity
Yena Cho, Jee Won Hwang, No-June Park, Junghyea Moon, Khan Hashim Ali, Young Ho Seo, In Su Kim, Su‐Nam Kim, Yong Kee Kim
Topics & Concepts
MitophagyReactive oxygen speciesCell biologyChemistryMitochondrionCell growthHomeostasisApoptosisBiochemistryBiologyAutophagySirtuins and Resveratrol in MedicineCalcium signaling and nucleotide metabolismAutophagy in Disease and Therapy