<p>CircRNAs: A New Chapter in Oral Squamous Cell Carcinoma Biology</p>
Hua‐yang Fan, Jian Jiang, Ya‐Jie Tang, Xin‐hua Liang, Ya‐ling Tang
Abstract
With the rapid development of bioinformatics and gene sequencing technologies, understanding of circular RNAs (circRNAs) has been extended, and numerous studies have identified the key regulator role of circRNAs in a variety of diseases, especially in cancer. Recently, accumulated studies of oral squamous cell carcinoma (OSCC) have discovered the great potential of circRNAs, which can serve as prognostic or diagnostic biomarkers and affect the development and therapy of OSCC. In this review, we detail the new progress of circRNA research for OSCC in order to provide new strategies for clinical diagnosis and treatment.
Topics & Concepts
Circular RNABasal cellmicroRNABiomarkerRegulatorCancer researchComputational biologyBiologyCancerBioinformaticsGeneMedicinePathologyGeneticsCircular RNAs in diseasesMicroRNA in disease regulationCancer-related molecular mechanisms research