Litcius/Paper detail

The Role of <i>mprF</i> Mutations in Seesaw Effect of Daptomycin-Resistant Methicillin-Resistant Staphylococcus aureus Isolates

Shengnan Jiang, Hemu Zhuang, Feiteng Zhu, Wei Xiang, Junxiong Zhang, Lu Sun, Shujuan Ji, Haiping Wang, Dandan Wu, Feng Zhao, Rushuang Yan, Yunsong Yu, Yan Chen

2021Antimicrobial Agents and Chemotherapy24 citationsDOIOpen Access PDF

Abstract

The emergence of daptomycin-resistant (DAP-R) Staphylococcus aureus strains has become a global problem. Point mutations in mprF are the main cause of daptomycin (DAP) treatment failure.

Topics & Concepts

BiologyMicrobiologyStaphylococcus aureusDaptomycinMethicillin-resistant Staphylococcus aureusPoint mutationMultidrug toleranceGeneticsMutationBacteriaGeneVancomycinBiofilmAntimicrobial Resistance in StaphylococcusAntibiotic Resistance in BacteriaInfective Endocarditis Diagnosis and Management
The Role of <i>mprF</i> Mutations in Seesaw Effect of Daptomycin-Resistant Methicillin-Resistant Staphylococcus aureus Isolates | Litcius