Primary nitro compounds: progress in the synthesis of isoxazoles by condensation with aldehydes or activated ketones
Francesco De Sarlo, Fabrizio Machetti
Abstract
-1,2-oxazine-3-carboxylates ("oxazinones"), by loss of alcohol instead of water. Isoxazole-4-carbaldehydes are obtained by the reaction of 3-oxetanone with primary nitro compounds.
Topics & Concepts
ChemistryNitroPrimary (astronomy)CondensationOrganic chemistryCombinatorial chemistryThermodynamicsAstronomyAlkylPhysicsChemical Synthesis and AnalysisSynthesis and Biological EvaluationChemical Synthesis and Reactions