Rational design of non-toxic GOx-based biocatalytic nanoreactor for multimodal synergistic therapy and tumor metastasis suppression
Lifeng Hang, Tao Zhang, Hua Wen, Meng Li, Lianbao Liang, Xinfeng Tang, Chunze Zhou, Junzhang Tian, Xiaofen Ma, Guihua Jiang
Abstract
GTZ@Z-RBM NPs can be used as an 'ON/OFF' intelligent nanoreactor to deliver GOx and TPZ for multimodal synergistic therapy and tumor metastasis suppression.
Topics & Concepts
NanoreactorChemistryGlucose oxidaseNanocarriersDoxorubicinMaterials scienceDrug deliveryNanotechnologyNanoparticleBiochemistryChemotherapyOrganic chemistryEnzymeMedicineSurgeryNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryCancer Research and Treatments