Guanidine hydrochloride (GuHCl)-catalysed microwave-mediated solvent- and metal-free synthesis of pyrimido[1,2-<i>a</i>]benzimidazole from aryl aldehyde and aryl methyl ketone
Rushikant Jagdale, Mohammad Zahid Hussain, K. N. Goswami, Ramalingam Peraman, Anupam Jana
Abstract
The rapid, eco-friendly, solvent- and metal-free microwave-assisted synthesis of pyrimido[1,2- a ]benzimidazole in high yields was achieved using the green organocatalyst guanidine hydrochloride using simple and inexpensive starting materials.
Topics & Concepts
GuanidineAldehydeArylBenzimidazoleKetoneChemistryHydrochlorideSolventMethyl KetoneMetalOrganic chemistryCatalysisAlkylChemistry and Chemical EngineeringMulticomponent Synthesis of HeterocyclesSynthesis and biological activity