Innovative dissolving microneedles for enhanced delivery of alpha arbutin and ascorbic acid: a novel LC–MS quantification approach
Ola Tarawneh, Sara Almasri, Ala A. Alhusban, Mohammad Hailat, Lama Hamadneh, Juhaina M. Abu Ershaid, Zeyad Hailat, Yahia F. Makableh
Abstract
This study presents a novel dissolving microneedle (MN) formulation designed to deliver alpha arbutin (AA) and ascorbic acid for hyperpigmentation treatment.
Topics & Concepts
Ascorbic acidArbutinDissolutionChromatographyAlpha (finance)ChemistryMaterials scienceNanotechnologyMedicineOrganic chemistryFood scienceSurgeryConstruct validityPatient satisfactionAdvancements in Transdermal Drug DeliverySalivary Gland Disorders and FunctionsPharmacological Effects of Natural Compounds