Updates in Drug-Related Pneumonitis Due to Targeted Oncologic Therapies
Kathy L. Chan, Saadia A. Faiz, Mehmet Altan, Ajay Sheshadri
Abstract
An increasing number of newer targeted oncologic therapies approved for clinical use can cause drug-related pneumonitis. Drug-related pneumonitis can be difficult to diagnose and requires a high index of suspicion. This review serves as an update to a prior review in this journal about pneumonitis with precision oncology therapies. In this review, we focus on the incidence, timing of onset, and imaging patterns of pneumonitis associated with a number of newly approved precision oncologic agents, with a particular focus on new antibody-drug conjugate therapies.
Topics & Concepts
MedicinePneumonitisDrugIntensive care medicinePharmacologyInternal medicineLungLung Cancer Treatments and MutationsHER2/EGFR in Cancer ResearchChronic Lymphocytic Leukemia Research