Fine tuning towards the next generation of engineered T cells
Thi Tham Nguyen, Patrick Ho, Sarah Staudt, Céline Grégoire, Kai Ziegler-Martin, Mégane Jassin, Alix Block, Michael Hudecek, J. Joseph Melenhorst, Jo Caers, Maik Luu
Topics & Concepts
Chimeric antigen receptorComputational biologyGenome editingEpigeneticsCell therapyImmunotherapyT cellGenetic enhancementComputer scienceAntigenPhenotypeCellBiologyGene deliveryTranscriptomeBioinformaticsSynthetic biologyNanotechnologyT-cell receptorKey (lock)GeneGenome engineeringElectroporationImmune systemMechanism (biology)ImmunologyEpigenesisReceptorMedicineGene deletionCAR-T cell therapy researchViral Infectious Diseases and Gene Expression in InsectsCRISPR and Genetic Engineering