Silver-mediated formal [4π + 2 <i>σ</i> ] cycloaddition reactions of bicyclobutanes with nitrile imines: access to 2,3-diazobicyclo[3.1.1]heptenes
Huijuan Liao, Jianyang Dong, Xuechen Zhou, Qin Jiang, Zhi Lv, Fang Lei, Dong Xue
Abstract
-hybridized nitrogen, 2,3-diazo-BCHepes can be expected to exhibit geometries similar to those of aza-BCHepes and much better solubility. We demonstrated the synthetic utility of our method by carrying out a scaled-up reaction and diverse postcatalytic transformations.
Topics & Concepts
NitrileCycloadditionDiazoChemistryCombinatorial chemistryOrganic chemistryCatalysisCyclopropane Reaction MechanismsSynthesis and Catalytic ReactionsOxidative Organic Chemistry Reactions