Synthesis and biological evaluation of coumarine-imidazo[1,2-c][1,2,3]triazoles: PEG-400 mediated one-pot reaction under ultrasonic irradiation
Rajkumar Samala, Satheesh Kumar Nukala, Ravinder Manchal, Vasudeva Reddy Nagavelli, Sirassu Narsimha
Topics & Concepts
ChemistryErlotinibADMELipinski's rule of fiveCycloadditionIC50Combinatorial chemistryIn vitroIn silicoEGFR inhibitorsStereochemistryNuclear chemistryEpidermal growth factor receptorOrganic chemistryReceptorBiochemistryGeneCatalysisClick Chemistry and ApplicationsSynthesis and biological activitySynthesis and Characterization of Heterocyclic Compounds