Synthesis of N-heterocyclic carbene gold(<scp>i</scp>) complexes from the marine betaine 1,3-dimethylimidazolium-4-carboxylate
Seyedeh Mahbobeh Mahdavi, Dirk Bockfeld, Rolf Büssing, Bianka Karge, Thomas Bannenberg, René Frank, Mark Brönstrup, Ingo Ott, Matthias Tamm
Abstract
S)AuCl] in the presence of potassium carbonate. The potential of the resulting mono- and dicarbene complexes to act as cytotoxic or antibacterial drugs was investigated.
Topics & Concepts
BetaineCarbeneCarboxylateChemistryMedicinal chemistryCombinatorial chemistryStereochemistryOrganic chemistryCatalysisSynthetic Organic Chemistry MethodsN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCatalytic Cross-Coupling Reactions