Nannocystin ax, an eEF1A inhibitor, induces G1 cell cycle arrest and caspase-independent apoptosis through cyclin D1 downregulation in colon cancer in vivo
Ying Hou, Rong Liu, Mengwei Xia, Chong Sun, Bingling Zhong, Jie Yu, Nana Ai, Jin‐Jian Lu, Wei Ge, Bo Liu, Xiuping Chen
Topics & Concepts
Cyclin D1Downregulation and upregulationCell cycleCell cycle checkpointG1 phaseApoptosisCyclin ECancer researchCyclin BCyclin ACell biologyCyclin A2Cyclin DCyclinBiologyChemistryBiochemistryGeneCancer-related Molecular PathwaysCancer Research and TreatmentsMicrotubule and mitosis dynamics