Head to head: should the intraductal component of invasive prostate cancer be graded?
Murali Varma, Jonathan I. Epstein
Abstract
The reporting of intraductal carcinoma of the prostate (IDCP) is controversial, with conflicting recommendations having recently been published by the International Society of Urological Pathology (ISUP) and the Genitourinary Pathology Society (GUPS). Both recommend that isolated (pure) IDCP should not be graded. However, the ISUP recommends incorporating the IDCP component of invasive prostate cancer in the Gleason score, whereas the GUPS recommends reporting IDCP as a comment, independently of the Gleason score. The arguments for and against incorporating the IDCP component of invasive prostate cancer in the Gleason score are discussed in detail.
Topics & Concepts
MedicineProstate cancerProstateGenitourinary systemCarcinomaUrologyOncologyCancerPathologyInternal medicineProstate Cancer Diagnosis and TreatmentProstate Cancer Treatment and ResearchUrologic and reproductive health conditions