Inhibition of LPS-induced Nox2 activation by VAS2870 protects alveolar epithelial cells through eliminating ROS and restoring tight junctions
Dan Li, Zhukai Cong, Cui Yang, Xi Zhu
Topics & Concepts
ARDSNicotinamide adenine dinucleotide phosphateCell biologyReactive oxygen speciesNADPH oxidaseA549 cellViability assayChemistryCellBiologyLungOxidase testBiochemistryMedicineEnzymeInternal medicineNeutrophil, Myeloperoxidase and Oxidative MechanismsImmune Response and InflammationNitric Oxide and Endothelin Effects