Modulating SQSTM1/p62-dependent selective autophagy of neurons by activating Nrf2 with multifunctional nanoparticles to eliminate α-synuclein aggregates and boost therapy of Parkinson’s disease
Hanghang Liu, Qing Yin Zheng, Jiaxin Yuan, Yifan Gao, Tingting Wang, Hao Zhang, Zhen Li
Topics & Concepts
AutophagyTFEBParkinson's diseaseChemistryKEAP1Cell biologyTranscription factorIn vivoAmyloid (mycology)BiophysicsDiseaseBiochemistryMedicineBiologyInternal medicineGeneBiotechnologyApoptosisInorganic chemistryParkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and TherapyCarbon and Quantum Dots Applications