Therapeutic correction of hemophilia A using 2D endothelial cells and multicellular 3D organoids derived from CRISPR/Cas9-engineered patient iPSCs
Jeong Sang Son, Chul‐Yong Park, Gyunggyu Lee, Ji Young Park, Hyo Jin Kim, Gyeongmin Kim, Kyun Yoo, Dong‐Hun Woo, Choongseong Han, Sang Kyum Kim, Han‐Jin Park, Dong‐Wook Kim, Jong‐Hoon Kim
Topics & Concepts
OrganoidCRISPRInduced pluripotent stem cellMulticellular organismMaterials scienceComputational biologyNanotechnologyCell biologyBiologyGeneticsEmbryonic stem cellCellGeneHemophilia Treatment and ResearchCAR-T cell therapy research