Baicalin inhibited both the Furin/TGFβ1/Smad3/TSP-1 pathway in endothelial cells and the AKT/Ca2+/ROS pathway in platelets to ameliorate inflammatory coagulopathy
Peichun Wang, Jiao Wu, Qiongsen Wang, Shaowei Zhuang, J. Zhao, Ying Yu, Weidong Zhang, Yuejuan Zheng, Xuan Liu
Topics & Concepts
BaicalinChemistryProtein kinase BPlatelet activationEndothelial dysfunctionPlateletPharmacologyCell biologyPhosphorylationMedicineEndocrinologyInternal medicineBiochemistryBiologyChromatographyHigh-performance liquid chromatographyFlavonoids in Medical ResearchBioactive Natural Diterpenoids ResearchTraditional Chinese Medicine Analysis