Fungal infections in immunocompromised critically ill patients
José Garnacho‐Montero, Irene Barrero-García, Cristina León-Moya
Abstract
Diverse pathogenic fungi can produce severe infections in immunocompromised patients, thereby justifying intensive care unit (ICU) admissions. In some cases, the infections can develop in immunocompromised patients who were previously admitted to the ICU. Aspergillus spp., Pneumocystis jirovecii, Candida spp., and Mucorales are the fungi that are most frequently involved in these infections. Diagnosis continues to be challenging because symptoms and signs are unspecific. Herein, we provide an in-depth review about the diagnosis, with emphasis on recent advances, and treatment of these invasive fungal infections in the ICU setting.
Topics & Concepts
MucoralesIntensive care medicineCritically illIntensive care unitMedicinePneumocystis jiroveciiAspergillosisMucormycosisAspergillusFungemiaHuman immunodeficiency virus (HIV)MycosisImmunologyBiologyMicrobiologyPathologyAntifungal resistance and susceptibilityFungal Infections and StudiesPneumocystis jirovecii pneumonia detection and treatment