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Pyrimido[1,2-a]benzimidazoles as inhibitors of oncoproteins ubiquitin specific protease 5 and MYCN in the childhood cancer neuroblastoma

Satyanarayana Gadde, Ane Kleynhans, Jessica K. Holien, Mohan Bhadbhade, Phuoc Linh Dan Nguyen, Ritu Mittra, Tsz Tin Yu, Daniel R. Carter, Michael W. Parker, Glenn M. Marshall, Belamy B. Cheung, Naresh Kumar

2023Bioorganic Chemistry11 citationsDOI

Topics & Concepts

NeuroblastomaGene knockdownDeubiquitinating enzymeCancer researchChemistryUbiquitinBenzimidazoleCancer cellIn vitroPediatric cancerCytotoxicityCell cultureCancerBiologyBiochemistryGeneGeneticsOrganic chemistryNeuroblastoma Research and TreatmentsHistone Deacetylase Inhibitors ResearchProtein Degradation and Inhibitors
Pyrimido[1,2-a]benzimidazoles as inhibitors of oncoproteins ubiquitin specific protease 5 and MYCN in the childhood cancer neuroblastoma | Litcius